Blar i Bergen Open Research Archive på forfatter "Vedeler, Christian Alexander"

Viser treff 1-12 av 12

    • Case Report: Limbic encephalitis following treatment with durvalumab for small-cell lung cancer 

      Moss, Thomas Totland; Stavem, Knut; Aandahl, Astrid; Gløersen, Anne S.; Grønberg, Bjørn Henning; Neumann, Kirill; Vedeler, Christian Alexander; Lundqvist, Christofer (Journal article; Peer reviewed, 2023-10-16)
      Background: Durvalumab is an immune checkpoint Inhibitor (ICIs) that is used in the treatment of malignant tumors, such as lung cancer and melanoma. ICIs are associated with immune-related adverse events including autoimmune ...

    • Case report: Pain in anti-DPPX encephalitis 

      Bjerknes, Tale Litlere; Steihaug, Ole Martin; Haugen, Mette; Hjelland, Ina Elen; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2022)
      Encephalitis due to antibodies targeting dipeptidyl-peptidase-like protein 6 (DPPX), a potassium channel subunit, is rare. The illness is typically characterized by a triad of weight loss, CNS hyperexcitability and cognitive ...

    • Case report: Seropositive myasthenia gravis complicated by limbic encephalitis positive for antibodies to AMPAR and Lgi1 

      Nes, Magne Solberg; Haugen, Mette; Haugland, Hans Kristian; Gilhus, Nils Erik; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2023-10-12)
      Objectives: Autoantibodies to the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) and leucine-rich glioma-inactivated 1 (Lgi1) are associated with autoimmune encephalitis. We described an acetylcholine ...

    • A cerebellar degeneration-related protein 2-like cell-based assay for anti-Yo detection in patients with paraneoplastic cerebellar degeneration 

      Erikstad, Kjell Inge; Herdlevær, Ida Ajvazi; Peter, Elise Marie; Haugen, Mette; Totland, Cecilie; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2023)
      Background and purpose Commercially available tests for Yo antibody detection have low specificity for paraneoplastic cerebellar degeneration (PCD) because these assays use cerebellar degeneration-related protein 2 (CDR2) ...

    • Cerebrospinal fluid proteome shows disrupted neuronal development in multiple sclerosis 

      Mosleth, Ellen Færgestad; Vedeler, Christian Alexander; Liland, Kristian Hovde; McLeod, Anette; Bringeland, Gerd Haga; Kroondijk, Liesbeth; Berven, Frode Steingrimsen; Lysenko, Artem; Rawlings, Christopher J.; El-Hajj Eid, Karim; Opsahl, Jill Anette; Gjertsen, Bjørn Tore; Myhr, Kjell-Morten; Gavasso, Sonia (Journal article; Peer reviewed, 2021-02-18)
      Despite intensive research, the aetiology of multiple sclerosis (MS) remains unknown. Cerebrospinal fluid proteomics has the potential to reveal mechanisms of MS pathogenesis, but analyses must account for disease ...

    • COVID-19 myocarditis and postinfection Bell’s palsy 

      Dahl, Elin Hoffmann; Mosevoll, Knut Anders; Cramariuc, Dana; Vedeler, Christian Alexander; Blomberg, Bjørn (Journal article; Peer reviewed, 2021)
      Here we present the case of a 37-year-old previously healthy man who developed fever, headache and a unilateral, painful neck swelling while working offshore. He had no known contact with anyone with COVID-19; however, due ...

    • CRMP5 Antibodies—Diagnostic Challenges 

      Totland, Cecilie; Haugen, Mette; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2021-09-22)
      CRMP5-associated paraneoplastic neurological syndromes (PNS) are rare, and only few studies describe larger cohorts of patients with CRMP5 antibodies. We have included 24 patients with CRMP5 antibodies and compared clinical ...

    • Development and Optimization of a Multilayer Rat Purkinje Neuron Culture 

      Uggerud, Ida Margrethe; Kråkenes, Torbjørn; Hirai, Hirokazu; Vedeler, Christian Alexander; Schubert, Manja (Journal article; Peer reviewed, 2023)
      Elucidation of the mechanisms involved in neurodegenerative diseases of the cerebellum has been hampered by the lack of robust single cell models to study Purkinje neurons and replicate at the same time in vivo features. ...

    • Limbic encephalitis following allogeneic hematopoietic stem cell transplantation 

      Johansen, Silje; Kråkenes, Jostein; Vedeler, Christian Alexander; Storstein, Anette; Reikvam, Håkon (Journal article; Peer reviewed, 2022)
      A woman with myelodysplastic syndrome (MDS) was treated with allogeneic hematopoietic stem cell transplantation (allo-HSCT). 65 days after the transplantation, she developed fatigue and central neurological symptoms. ...

    • Nevrosarkoidose – en pasientserie 

      Børhaug, Emilia; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2021)
      BAKGRUNN Nevrosarkoidose er en sjelden form for sarkoidose som affiserer nervesystemet. Formålet med studien var å kartlegge kliniske manifestasjoner, utredningsfunn og behandlingsstrategier hos pasienter med nevrosarko ...

    • Paraneoplastic and Other Autoimmune Encephalitides: Antineuronal Antibodies, T Lymphocytes, and Questions of Pathogenesis 

      Greenlee, John E.; Carlson, Noel G.; Abbatemarco, Justin R.; Herdlevær, Ida Ajvazi; Clardy, Stacey L.; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2022)
      Autoimmune and paraneoplastic encephalitides represent an increasingly recognized cause of devastating human illness as well as an emerging area of neurological injury associated with immune checkpoint inhibitors. Two ...

    • Serum neurofilament as a predictor of 10-year grey matter atrophy and clinical disability in multiple sclerosis: a longitudinal study 

      Lie, Ingrid Anne; Kacar, Sezgi; Wesnes, Kristin; Brouwer, Iman; Kvistad, Silje S.; Wergeland, Stig; Holmøy, Trygve; Midgard, Rune; Bru, Alla Nikolajevna S; Edland, Astrid; Eikeland, Randi; Gosal, Sonia; Harbo, Hanne-Cathrin Flinstad; Kleveland, Grethe; Sørenes, Yvonne; Øksendal, Nina; Varhaug, Kristin Nielsen; Vedeler, Christian Alexander; Barkhof, Frederik; Teunissen, Charlotte E.; Bø, Lars; Torkildsen, Øivind Fredvik Grytten; Myhr, Kjell-Morten; Vrenken, Hugo (Journal article; Peer reviewed, 2022)
      Background The predictive value of serum neurofilament light chain (sNfL) on long-term prognosis in multiple sclerosis (MS) is still unclear. Objective Investigate the relation between sNfL levels over a 2-year ...